WISCONSIN MEDICAL JOURNAL central Pontine Myelinolysis: case Series and review
نویسنده
چکیده
Doctor Musana is a general internal medicine resident and Doctor Yale is a general internal medicine physician with Marshfield Clinic, and Marshfield Clinic Research Foundation, Marshfield, Wis. Please address correspondence to: Steven H Yale, MD, General Internal Medicine, Marshfield Clinic, 1000 N Oak Ave, Marshfield, WI 54449; phone 715.387.9110; fax 715.389.3808; e-mail yale.steven@mcrf. mfldclin.edu. aBStract Objective: To review central pontine myelinolysis (CPM) and osmotic demyelination syndrome (ODS) and describe the clinical features, etiologic factors, and clinical outcomes of 6 patients diagnosed with CPM or ODS.
منابع مشابه
Osmotic demyelination syndrome.
Formerly known as central pontine myelinolysis, osmotic demyelination syndrome (ODS) is defined by a symmetrical destruction of myelin sheaths involving mainly the central portion of the basis pontis without evidence of vascular involvement. We report the case of a 60-year-old man who presented to the emergency department with a 2-week history of progressive confusion, memory loss, and lower ex...
متن کاملCentral pontine myelinolysis following orthotopic liver transplant: association with cyclosporine toxicity.
Central pontine myelinolysis can occur after orthotopic liver transplantation leading to high mortality and serious morbidity. In our case, central pontine myelinolysis was associated with wide fluctuations in cyclosporine levels during an episode of hypocholesterolaemia, which may have precipitated central pontine myelinolysis.
متن کاملCentral pontine myelinolysis in association with Hodgkin's lymphoma.
Central pontine myelinolysis was found histologically in a young man who died with Hodgkin's lymphoma. Clinically he had developed a progressive peripheral sensory deficit, ataxia, quadriparesis, dysarthria, incontinence and drowsiness. This is the fifth case reported in the British literature. The pathogenesis and aetiology of this primary demyelinating disease are considered.
متن کاملCentral myelinolysis in a patient with hyponatraemia.
We present a case of a 50-year old man who developed mutism and a flaccid quadriparesis within 48 hours of presentation to hospital with severe hyponatraemia. A diagnosis of central pontine myelinolysis was made based on the clinical features and typical appearances on magnetic resonance imaging.
متن کاملCentral pontine myelinolysis without hyponatraemia.
Central pontine myelinolysis is an acquired demyelinating disorder of uncertain origin that predominantly affects the centre of the basilar portion of the pons. Several theories have been proposed to account for this condition, prominent among them being abnormalities in serum sodium concentration. We report on a patient who had central pontine myelinolysis with extrapontine lesions and Wernick...
متن کامل